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Key Insights

Emergence of New Age Synthetic Materials Steering Market Growth

The procedure of bone grafting has witnessed gradual shift from traditional allogenic and autologous bone grafts to synthetic based bone grafts. The emergence of this new biological enhanced material assists in regeneration while minimizing the usage of autografts during surgeries.

The ongoing development to incorporate effective properties from different materials into an biological enhanced graft products is leading the market growth. For instance,  Kuros Biosciences has developed a new synthetic bone graft substitute known as MagnetOs. This product comprises of submicron surface topology which assists in regeneration of bone tissues. The product primarily comprises of hydroxyapatite and tricalcium phosphate. The product has been approved in the European region for void filling application in orthopedic and dental surgeries. Similarly,  it has been approved in the U.S. as graft extender for spinal fusion. Thus, emergence of effective synthetic materials is likely to drive the marker growth over the coming years.

Rising Dental Surgeries Pushing Market Growth

The rising cases related to dental procedures especially in the U.S. is pushing the market growth for bone grafts and subsitiute products. As per the stats released by the U.S. Department of Health and Human Services, nearly one third of the American population suffer from dental problems. This has boosted the establishment of dental firms in the country at significant rate.

For instance, number of dental establishments in the U.S. increased from 113,218 in 2002 to 125,151 in 2012. Therefore, rising cases of dental related problems coupled with ongoing establishment of dental firms is likely to positively influence the market growth 9ver the coming years.

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Product Outlook

On the basis of product, the market is bifurcated into allografts and synthetic. Within this category, synthetic product segment is likely to observe swift growth over the forecast period. The synthetic product segment is further segmented into ceramic, composite, polymer, and bone morphogenetic proteins (BMP). The synthetic based grafts offer many advantages such as increased biocompatibility, reduce chances of disease transmission, lower surgical time, and many more. Owing to the aforementioned properties, the segment is expected to project higher growth rate compared to its counterpart.

Allografts product segment is anticipated to dominate the market share in 2019. The segment is further broken down into demineralized bone matrix and others category. The use of this product segment provides rapid healing and offers enhanced structural support. In addition, the product segment is largely used in surgeries related to hip, spine, and knee without the need to harvest bone. Therefore, owing to the properties related to the product segment is expected to drive its demand over the predicted timeline.

Application Outlook

On the basis of application, the market is segmented into dental, craniomaxillofacial, joint reconstruction, foot & ankle, spinal fusion,  and long bone. Within this segment, spinal fusion application is expected to emerge as the dominant category over the forecast period. The rising number of geriatric population coupled with increasing prevalence of De novo degenerative lumber scoliosis (DNDLS) within this age group is pushing the market growth for spine grafts. The spine grafts is considered as a effective method for the treatment of these spinal deformities.

The dental application segment is expected to observe swift growth over the forecast period. The rising cases of tooth extraction coupled with delayed socket preservation is fueling the market growth for this segment. For instance, in Germany alone, nearly 9 million of the adult population undergoes tooth extraction procedure. However, delay in socket preservation post extraction often results in loosening of 50% of the hard and soft tissue volumes and thus ultimately leading to bone grafting procedure.

Competitive Landscape

The key vendors of the industry are Zimmer Biomet, Wright Medical Group N.V., Stryker Corporation, Smith & Nephew Inc., Orthofix Holdings Inc., Nuvasive Inc., Kuros Biosciences, Baxter, DePuy Synthes Inc., and AlloSource.

The industry vendors are focused on developing effective synthetic materials and enhancing market presence. For instance, in 2018, Nuvasive Inc. launched a ceramic based bone graft called AttraX. Similarly, Medtronic launched a new product for spine surgeries called Infuse in 2018.


The material required to perform bone grafting surgical procedure that assists in replacement or repairing of bone structures is known as bone grafts and substitutes

Global Bone Grafts and Substitutes Market Segmentation

By Product


       --Demenaralized Bone Matrix






       --Bone Morphogenetic Proteins

By Application



       -Joint Reconstruction

       -Foot and Ankle

       -Long Bone

       -Spinal Fusion

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