This report is built using data and information sourced from proprietary databases, primary and secondary research and in-house analysis by GBI Research's team of industry experts.
Cell culture technology is used to carry out processes external to the natural environment by maintaining controlled environments which enable the growth of various cell cultures for use in medicine and research. The processes is related to methods involved in the development of tissue or organ cultures. Multicellular eukaryotic cells from animals are usually preferred for cell culture as they provide standard characteristics for growing environments. Plant cells are the second choice for culture technology, while fungi, bacteria, protists and others are also used for the developmental process.
The development of recombinant methods involves genetic manipulation and restructuring of DNA or genes. Genetic recombination usually takes place in a biological environment, while DNA recombination occurs either during a repair response or experiments using in vitro studies. This is also known as genetic engineering technology and was developed at the end of the twentieth century. This method was further developed for large-scale cell culture production and was found to be helpful in protein synthesis processes, such as insulin production.
GBI Research indicates that the cell culture market is growing continuously due to increased demand for biopharmaceutical products. The introduction of biosimilars across various geographies in the forecast period on a large scale will boost the cell culture market, rapidly. Despite concerns about low flexibility for manufacturing quantities and other factors, the higher efficacy of the end products will drive its growth in the future.
Scope of this Report:
Reasons to Get this Report:
- Analysis of various technologies involved in cell culture and the key associated manufacturing processes involved
- Key drivers and barriers that have a significant impact on the cell culture market.
- Major equipment, cell banks and cell lines for cell culture development have been analyzed
- Annualized market data for the media, sera, reagents and global cell culture market from 2004 to 2011, forecast forward to 2018, have been provided in the report.
- Major players in the cell culture market are enlisted providing their company overview and company roles in the market.
- Align your product portfolio to the markets with high growth potential
- Develop market-entry and market expansion strategies by identifying the leading therapeutic segments and geographic markets poised for strong growth
- Develop strategic initiatives by understanding the key focus areas of leading companies
- Exploit in-licensing and out-licensing opportunities by identifying products that could fill portfolio gaps
GBI Research, the leading business intelligence provider, has released its latest research "Cell Culture - Rising Demand for Biologics and Growing Visibility of Approval Pathway for Biosimilars will Create Growth Opportunities", which provides in-depth analysis on the processes, drivers and barriers of the cell culture market. The report analyzes the role of biopharmaceutical products that basically provide enhancement to media, sera, reagents and cell culture market. Major manufacturing technologies involved in the cell culture technology have been detailed in the report. Furthermore, the report provides competitive benchmarking for the leading players that shape the global media, sera, reagent and overall cell culture market.
1 Table of Contents
1 Table of Contents
1.1 List of Tables
1.2 List of Figures
2 Cell Culture - Introduction
3 Cell Culture - Overview
3.2 Cell Lines
3.3 Application of Cell Lines
3.3.1 Characteristics of Cell Lines
3.4 Selective Cell Lines
3.4.1 Chinese Hamster Ovary
3.4.2 SP2/0 and NS0
3.4.3 HEK 293 and PER. C6
3.5 Transformational Approach of Transgenic Model
3.5.1 Transgenic DNA Preparation
3.5.2 Insertion of the Transgenic DNA into Animals
3.5.3 Clone and Integrity Verification of the Transgene
3.5.4 DNA Purification and Establishing a Screening Method
3.5.5 Breeding and Analysis of Transgenic Rodents
3.6 Stem Cell Research has Enormous Potential for Cell Culture
3.6.1 Applications of Stem Cell Research
3.6.2 Stem Cell Research Market Analysis
3.7 Fermentation Methods
3.7.1 Fed-Batch Fermentation
3.7.2 Important Factors for Regulating Cell Culture
3.8 Fermenters and Bioreactors
3.8.2 Selection of Bioreactors
3.8.3 Batch Bioreactor
3.8.4 Continuous Bioreactor
3.8.5 Submerged Bioreactors - Stirred Tank
3.8.6 Airlift Bioreactor
3.8.7 Water-Jacketed Bioreactor
3.9.1 Role of Media
3.9.2 Types of Media
3.10.1 Sources of Sera
3.10.2 Sera Safety and Regulations
3.10.3 Shift to Serum Free Media
3.11.1 Major Types of Biologic Reagents
3.11.2 Reagent Safety Issues
4 Cell Culture - Current and Future Trends
4.1 Cell Culture Market Forecast
4.2 Media Market Forecast
4.3 Sera Market Forecast
4.4 Reagents Market Forecast
4.5 Drivers and Restraints for Cell Culture Market
4.5.1 Drivers for Cell Culture Market
4.5.2 Restraints for Cell Culture Market
5 Cell Culture - Biopharmaceuticals an Important Part of Cell Culturing
5.1 Genetic Modifications
5.1.1 Cell Culture Life-Cycle Expressions
5.1.2 Biotechnological Product Development Using Cell Culture Method
5.1.3 Cell Banking and Seed Culture
5.1.4 Cell Systems
5.1.5 Advantages and Disadvantages of Cell Culture Techniques
5.2 Cell Lines and Banks
5.2.1 Manufacturing of Biopharmaceuticals using Cell Culture Techniques
5.2.2 Standard Methods for Cell Culture
5.2.3 Validation and Quality Maintenance
5.2.4 Essential Guidelines for Maintaining Sterilization Standards
5.3 Successful Treatments from Biopharmaceuticals is Increasing the Demand for Cell Culturing
6 Key Players in the Culture Media, Sera and Reagents Market
6.1 Cell Culture Suppliers' Market Share
6.1.1 Life Technologies Corporation
6.1.2 Sigma-Aldrich Corporation
6.1.3 Thermo Fisher Scientific Inc.
6.1.4 Affymetrix, Inc.
6.1.5 BD Biosciences
6.1.6 EMD Millipore
6.1.7 Advanced Biotechnologies, Inc.
6.1.9 Analytical Biological Services Inc.
6.1.10 Athena Biotechnologies, Inc.
6.1.11 Biochrom AG
6.1.12 Bioreclamation, Inc.
6.1.13 Cell Essentials, Inc
6.1.14 CellGenix Technologie Transfer GmbH
6.1.15 Clontech Laboratories, Inc.
6.1.16 Gemini Bio-Products
6.1.17 Lonza BioSciences Singapore Pte Ltd
6.1.18 Mediatech, Inc.
6.1.19 MP Biomedicals, LLC
6.1.20 PAA Laboratories GmbH
6.1.21 Quality Biological, Inc.
6.1.22 R&D Systems, Inc.
6.1.23 SAFC Biosciences, Inc.
6.1.24 Selexis SA
6.1.25 SeraCare Life Sciences, Inc.
6.1.26 Sera Laboratories International Ltd.
7 Cell Culture - Appendix
7.1 Market Definitions
7.4 Research Methodology
7.4.2 Secondary Research
7.4.3 Primary Research
7.4.4 Expert Panel Validation
7.5 Contact Us
List of Tables
1.1 List of Tables
Table 1: Cell Culture, Basal-Media Components, 2011
Table 2: Cell Culture, Examples and Applications of Specialty Media, 2011
Table 3: Cell Culture, Validation Test for Sera Approval, 2011
Table 4: Cell Culture, Global, Revenue ($bn), 2004-2011
Table 5: Cell Culture, Global, Revenue ($bn), 2011-2018
Table 6: Cell Culture, Media Market Revenues, Global ($m), 2004-2011
Table 7: Cell Culture, Media Market Revenues, Global ($m), 2011-2018
Table 8: Cell Culture, Sera Market Revenues, Global ($m), 2004-2011
Table 9: Cell Culture, Sera Market Revenues, Global ($m), 2011-2018
Table 10: Cell Culture, Reagent Market Revenues, Global ($bn), 2004-2011
Table 11: Cell Culture, Reagent Market Revenues, Global ($bn), 2011-2018
Table 12: Cell Culture, Manufacturing Models, 2011
Table 13: Cell Culture, Comparison of Therapeutic Protein Production across Different Systems, 2011
List of Figures
1.2 List of Figures
Figure 1: Cell Culture, Transgenic Model, Process Steps, 2011
Figure 2: Cell Culture, Applications of Stem Cell Research, 2011
Figure 3: Cell Culture, Stem Cell Research, Porter's Five Force Analysis, 2011
Figure 4: Cell Culture, Fermentation Cycle, 2011
Figure 5: Cell Culture, Batch and Fed-Batch Fermentation, 2011
Figure 6: Cell Culture, Upstream Processing in Biopharmaceuticals, Tray Bioreactor, 2011
Figure 7: Cell Culture, Upstream Processing in Biopharmaceuticals, Stirred Tank Bioreactor, 2011
Figure 8: Cell Culture, Global, Revenue ($bn), 2004-2018
Figure 9: Cell Culture, Media Market Revenues, Global ($m), 2004-2018
Figure 10: Cell Culture, Sera Market Revenues, Global ($m), 2004-2018
Figure 11: Cell Culture, Reagent Market Revenues, Global ($m), 2004-2018
Figure 12: Cell Culture, Market, Drivers and Restraints, 2011
Figure 13: Cell Culture, Cell Bank System, 2011
Figure 14: Cell Culture, Suppliers Market Share, Global, 2011
Figure 15: Cell Culture, Life Technologies Corporation, Business Overview, 2011
Figure 16: Cell Culture, Sigma-Aldrich Corporation, Business Overview, 2011
Figure 17: Cell Culture, Thermo Fisher Scientific Inc., Business Overview, 2011
Figure 18: Cell Culture, Affymetrix, Inc., Business Overview, 2011
Figure 19: Cell Culture, BD Biosciences, Business Overview, 2011
Figure 20: Cell Culture, EMD Millipore, Business Overview, 2011
Figure 21: Cell Culture, Advanced Biotechnologies, Inc., Business Overview, 2011
Figure 22: Cell Culture, Amresco Inc., Business Overview, 2011
Figure 23: Cell Culture, Analytical Biological Services Inc., Business Overview, 2011
Figure 24: Cell Culture, Athena Biotechnologies, Inc., Business Overview, 2011
Figure 25: Cell Culture, Biochrom AG, Business Overview, 2011
Figure 26: Cell Culture, Bioreclamation, Inc, Business Overview, 2011
Figure 27: Cell Culture, Cell Essentials, Inc., Business Overview, 2011
Figure 28: Cell Culture, CellGenix Technologie Transfer GmbH, Business Overview, 2011
Figure 29: Cell Culture, Clontech Laboratories, Inc., Business Overview, 2011
Figure 30: Cell Culture, Gemini Bio-Products, Business Overview, 2011
Figure 31: Cell Culture, Lonza BioScience Singapore Pte Ltd, Business Overview, 2011
Figure 32: Cell Culture, Mediatech, Inc., Business Overview, 2011
Figure 33: Cell Culture, MP Biomedicals, LLC, Business Overview, 2011
Figure 34: Cell Culture, PAA Laboratories GmbH, Business Overview, 2011
Figure 35: Cell Culture, Quality Biological, Inc., Business Overview, 2011
Figure 36: Cell Culture, R&D Systems, Inc., Business Overview, 2011
Figure 37: Cell Culture, SAFC Biosciences, Inc., Business Overview, 2011
Figure 38: Cell Culture, Selexis SA, Business Overview, 2011
Figure 39: Cell Culture, SeraCare Life Sciences, Business Overview, 2011
Figure 40: Cell Culture, Sera Laboratories International Ltd., Business Overview, 2011
Companies Mentioned in this Report
Life Technologies Corporation
Thermo Fisher Scientific Inc.
Advanced Biotechnologies, Inc.
Analytical Biological Services Inc.
Athena Biotechnologies, Inc.
Cell Essentials, Inc
CellGenix Technologie Transfer GmbH
Clontech Laboratories, Inc.
Lonza BioSciences Singapore Pte Ltd
MP Biomedicals, LLC
PAA Laboratories GmbH
Quality Biological, Inc.
R&D Systems, Inc.
SAFC Biosciences, Inc.
SeraCare Life Sciences, Inc.
Sera Laboratories International Ltd.
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